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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e721f380e183f04cb5126daef8142f4de14733c02c14511010321d439c109a73' 
  AND token = '0Tw9B/finNu3aQVC5bhi7s4oZRfee7Uqo96n6HlWrBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}