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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0440a98f866a3fad2e2b4685d27b363850e0fb9a8414ec57f2e21fe45c5732' 
  AND token = 'M528hzOybyaYW4yFsvdnr4xzOez40mUiHRhawHWFlz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}