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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b41c8a0047160274176fcdf99b485060a658840903a539c3f48430be5b88afa5' 
  AND token = 'qv5aqd4asUa5nqEKKrlgvqXGya2twxsdzt4IRLtok04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}