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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d2e71127c8e4337d5fd49f3608ec2a30420daaec456ce23e11ed0b55f7315e4' 
  AND token = 'sVlHo5Fv267RAE2+GySIjUY4hUgzzdSoZ7VLCH36L9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}