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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645f06f10c15750ca85aebe3b585265d0e34831e54fbed2ed536c662d8035e25' 
  AND token = 'n4+0ByQF6TDP8k6u5AH9M1q6Y3z5ApdG5dnrNTBysBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}