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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbd823ba3e37d55ab5b332429faf2e187bde65c6f765bf93511b61e8439ab7c6' 
  AND token = '4MNuixwZUTCm2NVmrgQo2V8Udu6B1pMr8vMzFxsPtGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}