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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c42d5b9c25867642e23d066feb22f0c4c6f653bb304caccf1e0761c4c99181b' 
  AND token = 'oFlQLRXeVbVByrecKgv1JLTt4kAFt0i9gog52mjfNqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}