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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b50c44b63aae76b4543f4c8bcbf4b3825ee393e147b5c79d1c64d49d902370c' 
  AND token = 'XhM+EUb7xHUvCPLG1VH2SGI0UHShHSGRZSa9A20OZR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}