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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2265b7a99b75ac8f2826222939ff2f35c375b423a29fa6537a4e5c8caeed7e4e' 
  AND token = '6bi/cIvNUToukDoLDdLQXdTQyW/OVpDAQCXBoYafsOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}