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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a3e1d8a5272d91c58ec06d33ae8e415d33b0658ed399b00652129a68ecc1714' 
  AND token = '0xDe8kHQp+FS4T9xyUVCcVJfIDXqJXDJeuQqlpo1q70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}