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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b977bd61865cd19c192bf12097426fe41f7d0e8e0f6ecdff019839a504c20e4' 
  AND token = 'IwxTgA2s0BCLAJCQ0YnAf2TSJofbp4cTfgF4LAksTGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}