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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '620f17491d12b2bc05fe80dece1fc43a6d577d1c870612d75edd742ef679c773' 
  AND token = '3LGh53k4n/Dam0XA+tdXneJcmJ5XAwiUJE6dk3MWLy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}