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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e346620a482f9d8d803a7df3655211f6a2212c3815b61481ab1a81ba8713510c' 
  AND token = 'bWYTy0cyjMTQt1CrntLOP6fesMWb5OjsgU1bt/zo7yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}