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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '488791bebaf2e0e52a91f7442490a6a1ee394ff0e328766dd08ca793250851a4' 
  AND token = '0IO1rk1a8uvlT0PCOBTda8G8h3CT92OYOmjnC+YKtpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}