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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd34decc482d8b5d68559bcd4fad81383d08d087eaaa8bf559c4e598049b9cb4b' 
  AND token = 'Rdd/ngaVQfcszeHeZ3/Sj4UuQyXOg5vzPN30SsiKjP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}