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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a11e475b6dd163b58e9e29a76bd459a0088d3b68cadf78b87addf1d4eb196af1' 
  AND token = 'p+MSGVjZ+rAGUZTU76W2A1mc1opMZhS6VoY3C9tZDgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}