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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '533500d0cd1b42365a40f355e1be27c3f0bceb366a6cef333bf4c673b30e5cb7' 
  AND token = 'DxD7S4VU2leJz8TKXdv844NK9Kw637eZulY0n2Th+Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}