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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa5e5fde5ee4cf5a4b28d91feb6266f86b1c27c409540e8aa67829620c378b66' 
  AND token = '/jA0ulnZhWGxd9WKKDsdW1QoWT5U5C9uBRyGjp1AE9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}