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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a7b409c246c88ea9e6f8f39bc0df97607d57fbf19a1688d52053a0fa1398619' 
  AND token = 'L6Non3rwQe+CtUEUGBS9C3NWSAoindka9LczOxd6jBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}