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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f4095e188c9745e7c025235c1c9d01635398ee0cacdb2fe6e58ff2514de1fd6' 
  AND token = 'G46J/2l6issMbF9HX+IVWtMqW2DLRKtSVIZ4yHnVbzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}