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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef47336db6de1348d8ba107f6fbf3bd59253bd6d688a654f80af6f83a802d391' 
  AND token = 'VjBmSaYyMGfJK4cnV4hnHdWB8OuwR7NpUI0SG5ZTMVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}