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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2599f77bc861a20feb5da50a365171b79d0c87f1709704d821bf82181c040c06' 
  AND token = '3bWnYlNOZ8hMlbWcJYG6A0eMuGr8Aww9XSZ/LjgBZhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}