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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8c3de39aa03cd6d88c4244b1aace750634c8b091b24e15d178694864ed32211' 
  AND token = 'UKZ1gU1W5oorz0CmAhv3Gg/N1baW8JwinCSYZFT9yz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}