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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bd85e1efd9fd7badb975d91e4da1332acb39179fe8679c21f903dbab05d9c12' 
  AND token = 'LUezfeX9kpzGA8aNOPlZtxvsKyNLX0pN7+hAbjUeJ8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}