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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d5ad009bb7788aceb18c89ed3a8e488e26dca9f014b3ccacd6e1ed272169e8e' 
  AND token = '++Je+/8ZSJXvoesWJH1HNwnPWOoib7DKTkZDn/6qURc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}