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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb83fc222efcfeb3ed5195dcb0a63193b4c5e25b56ddf73856bee1d9b02ba0f' 
  AND token = 'JuJk0szy2+HKj2Lm9cfuc7UvH3dKY9+KBjpj4ftAEKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}