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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e771c7aba42a2f60458050f1594070969191abfc1ba9f3d3d39e07dcfd643a6' 
  AND token = 'ymfUVermeGbEcGzG6xM9aplx25umEjcbVxz2YeIwCcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}