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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7518526cb8a4b95836b24669dbd91898c74a3e4c8be7d8a64b29561ed96dac56' 
  AND token = 'Ev86x+rrzsU2RMJPoPRf7jMjAXN7H3obwx3EWOKS1aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}