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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0efaf67c326e9e7d92c1f5ff018bb115824675cc702eb6f32b4e209a59ba2cd' 
  AND token = 'ZErNGSeCI7/0HHhhKwLrYuHoOup11lrOHhsoB72Xpeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}