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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f23b9caafed8eca4d41bad7495b291e26d346ce554637e491b2b6278e58cf0b' 
  AND token = 'qvkzb+FkJp6PxrE+QkNdbQZHQnqjUFnw8z/sxPTQ0T0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}