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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e6f1d40f7d63b9332b086ba93a5a2be34bf243380609d266e53016ec5f4ad96' 
  AND token = 'iv5RaqewdFRaqkifSv9QGxqq2BRWB3lwRX4+EM5Bna4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}