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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6525730e5bc57e610e377a85606f5e2c8e943373e59fec010543e5cceb01f694' 
  AND token = 'DN6k17eLHqKInYLfN0f01wZdixq8xZvtNOWu90TCZZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}