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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b4db541105add8d6dbc2d4f09fd6bd4c0515d1ec7ec635a7e8c4ffda4bcf77b' 
  AND token = 'EWG0GbQS2mkI86o8WnwxV3YwegLiSbKSnPySq2ZbeXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}