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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c4dca827bd4d5d7fd210edca3b1bdfb0c28270107d381b24ab4073f0dea8e90' 
  AND token = 'H4ot5Uq5kbOLBq/MoLKcAx5ADB0/ihNJoZMGczO+Dng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}