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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1745ff91482b765cf332b1961c3afdc4fc77a4fe5f158d5fdd36e2e7e6044f01' 
  AND token = '2hjDQWyISEWpj81lpPWFT31e6TfxJhb79Qqh/QXUEaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}