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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf75ed2b848a3bb91deeb3c238b0790ae1ec35b2ea05d8b8ac5101225f7fa75a' 
  AND token = 'e6/uxFyOX3TgeM689lSTf4ncZLC55skIuxNHj5UWwMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}