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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ecc89dfe37fd83bcb50358e6f3fc9267f76d4d4d2a051332987a4b5d6d7154f' 
  AND token = 'B9n7lW2epHcQR+0hA3GZkJrn6aVry4bkUYycrEwkxnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}