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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b81b5209403db09ce7640b3ddf30eb9a599b6f7ef11b4708ab4a90e95ceac28' 
  AND token = '/hrZdjucGgL44xKKAvHiuG+MGLd7s1tf0kzdP3kOOOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}