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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '770e9deaedd0e00aecea3f729a5f9a7d8593005401b43511fdbb3f103c08714c' 
  AND token = 'b/0pN0CzVdKEPrJCgVu9+arg30kTOnufNXVbAh+3cP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}