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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed4321fca13dee5453a9ca719822a4286bada93f6bc3692e9b57303a89726a48' 
  AND token = '8qPRyjnGTAQfHyi3oZFLFXqQSLOPb/bD8v8oq2vrwqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}