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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2a4ded39639e3b28363076f9ee8e36841208edca394e02efc180569fba4dab' 
  AND token = 'xgW+vt97jKAzRmXyqkFmClIAnedVvb/svHpK4I6TB+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}