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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53e1c5ebaee9d27ba8d5bf7373a5c86e4c1d6697c68914da26405002a34a39a' 
  AND token = '/X2CQ+vWCsu7jJCeOt+RhMtP+kvB+XA8t53W16wWTns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}