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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73e42fc10b43d2decb56bdffe55cddf93368f766e5249362d57419f57dbd1f36' 
  AND token = 'GF5V8jcSp/9+saW1I3r4ZMpn3qieGyAzsBni2qSYddo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}