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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd77514280e901e0a8eaa9624a248272c1cde2609831e3c9a24f3bfb117fa2e9c' 
  AND token = 'PpnZvtEKxZa+DgmiLgB+3SUB5NyxFlbHPvQaOnwF3Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00091

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}