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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b9872bb6431edd3f04dc1c6d4f4feb25768ca0b5c69004f1c76cb8d4dfaded' 
  AND token = 'bp0OxDMIo5dIFAl5UwpmfwErplud3VI+nRRCX8zcjFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}