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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a1bf13cf130d28822a3eec3231e9ef40b49e4152e7fc42d2a3550bf6b3f553' 
  AND token = '0w2yDR8GoNbH1p+V/qu5q8i/wBz3j1MF7QmnITDuNWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}