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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3aa8a4b3e766246dc1659855aa064e2b1ad6d6dd5f89016f4913216cb55c2f1' 
  AND token = 'UKPCCQb+uq4BmLlFIIktyqpEC44kdbA5W6Yq09z3zy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}