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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38100e425aef29b932aef9fd856c04ffc249e2ef9b6e44c43973b19090484fe0' 
  AND token = 'Em4Ui6+G1/mkYv5HJTl6RP7iAWngnRnDavec48wSuOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00081

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}