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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c7546f11e65321259994a98ae68c43b5daa9e533ada7427225034823cf19525' 
  AND token = 'TZyrVBZONWCcwey4hh3cGMtELN0DOTkoVrCc3gmtqcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}