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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37aa344b0226968b118cf11345c9868fca0901b86b6cd97052862f6266cd3a2d' 
  AND token = 'uZJ4rosp+1kN3NFhNA1i3/CGJrkC+RYYGcr0GEN/OVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}